• In a large bowl, combine the water and yeast.
• Stir until dissolved and let it set for 3-5 minutes (it should become foamy as the yeast activates).
• In a microwaveable bowl, add sugar, whole milk, salt, powdered milk, vanilla extract, and butter. Heat in the microwave for a few seconds, stirring occasionally until the butter has melted, but it's not hot enough to kill the yeast.
• If the butter and milk mixture is cool enough, pour it into the yeast mixture, add eggs, and stir well.
• Gently add the flour a cup at a time. Mix well with hands or a stand mixer. The dough should be sticky, but add more flour a little at a time if it's too sticky. Less flour is preferable.
• Knead the dough for a minute or two. Cover loosely with a clean cloth and let rise in a warm, draft-free place for 1½-2 hours or until doubled.
• Make cinnamon sugar by combining sugar, cinnamon, and nutmeg. Set aside until ready to use.
• Punch the cinnamon roll dough down. Lightly flour a board or work surface, then roll the dough out into a 1-inch thick rectangle. Generously brush with melted butter. Leaving a 1-inch border on the dough, evenly sprinkle it with cinnamon sugar. Pat the cinnamon sugar gently so it sticks to the surface.
• Starting with the end nearest you, roll the dough up snugly like a jelly roll around the filling, finishing the roll with the seam side down. Don't forget to pinch it so it seals together and doesn't come apart when transferring it to a baking sheet.
• Slice the roll into 4 equal pieces, then slice each piece into 3 equal pieces for a total of 12 rolls.
• Grease the bottom of the baking pan with butter or use a cooking spray. Place the cinnamon roll slices close together in the pan and let rise until doubled, about 45 minutes. Bake at 350℉ (180℃) for 25-30 minutes or until golden browned. Remove from the oven and let cool for about 5 minutes.

Cream Cheese Glaze

• Whip the cream cheese, powdered sugar, vanilla, and 2-3 tablespoons of milk until very creamy. Add more milk if needed to get the desired drizzling consistency. Drizzle over the cinnamon bun, and serve warm.